Evidence for a catabolic role of glucagon during an amino acid load.

@article{Charlton1996EvidenceFA,
  title={Evidence for a catabolic role of glucagon during an amino acid load.},
  author={Michael R. Charlton and Deborah Adey and K Sree Nair},
  journal={The Journal of clinical investigation},
  year={1996},
  volume={98 1},
  pages={90-9}
}
Despite the strong association between protein catabolic conditions and hyperglucagonemia, and enhanced glucagon secretion by amino acids (AA), glucagon's effects on protein metabolism remain less clear than on glucose metabolism. To clearly define glucagon's catabolic effect on protein metabolism during AA load, we studied the effects of glucagon on circulating AA and protein dynamics in six healthy subjects. Five protocols were performed in each subject using somatostatin to inhibit the… CONTINUE READING