Evidence for a Shared Mechanism in the Formation of Urea-Induced Kinetic and Equilibrium Intermediates of Horse Apomyoglobin from Ultrarapid Mixing Experiments.

Abstract

In this study, the equivalence of the kinetic mechanisms of the formation of urea-induced kinetic folding intermediates and non-native equilibrium states was investigated in apomyoglobin. Despite having similar structural properties, equilibrium and kinetic intermediates accumulate under different conditions and via different mechanisms, and it remains… (More)
DOI: 10.1371/journal.pone.0134238

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@article{Mizukami2015EvidenceFA, title={Evidence for a Shared Mechanism in the Formation of Urea-Induced Kinetic and Equilibrium Intermediates of Horse Apomyoglobin from Ultrarapid Mixing Experiments.}, author={Takuya Mizukami and Yukiko S Abe and Kosuke Maki}, journal={PloS one}, year={2015}, volume={10 8}, pages={e0134238} }