Evidence for a Golgi-to-Endosome Protein Sorting Pathway in Plasmodium falciparum

  title={Evidence for a Golgi-to-Endosome Protein Sorting Pathway in Plasmodium falciparum},
  author={Priscilla M Krai and Seema Dalal and Michael Klemba},
  booktitle={PloS one},
During the asexual intraerythrocytic stage, the malaria parasite Plasmodium falciparum must traffic newly-synthesized proteins to a broad array of destinations within and beyond the parasite's plasma membrane. In this study, we have localized two well-conserved protein components of eukaryotic endosomes, the retromer complex and the small GTPase Rab7, to define a previously-undescribed endosomal compartment in P. falciparum. Retromer and Rab7 co-localized to a small number of punctate… CONTINUE READING


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