Evidence for a “Wattle and Daub” Model of the Cyst Wall of Entamoeba

@inproceedings{Chatterjee2009EvidenceFA,
  title={Evidence for a “Wattle and Daub” Model of the Cyst Wall of Entamoeba},
  author={Anirban Chatterjee and Sudip Ghosh and Ken Jang and Esther Bullitt and Landon L. Moore and Phillips W. Robbins and John Samuelson},
  booktitle={PLoS pathogens},
  year={2009}
}
The cyst wall of Entamoeba invadens (Ei), a model for the human pathogen Entamoeba histolytica, is composed of fibrils of chitin and three chitin-binding lectins called Jacob, Jessie3, and chitinase. Here we show chitin, which was detected with wheat germ agglutinin, is made in secretory vesicles prior to its deposition on the surface of encysting Ei. Jacob lectins, which have tandemly arrayed chitin-binding domains (CBDs), and chitinase, which has an N-terminal CBD, were each made early during… CONTINUE READING

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An Entamoeba cysteine peptidase specifically expressed during encystation.

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