Evidence for Spinal Conditioning in Intact Rats

@article{Joynes1997EvidenceFS,
  title={Evidence for Spinal Conditioning in Intact Rats},
  author={R. Joynes and Paul A. Illich and James W. Grau},
  journal={Neurobiology of Learning and Memory},
  year={1997},
  volume={67},
  pages={64-68}
}
Prior work suggests that spinal systems are sensitive to the stimulus relationships that underlie Pavlovian conditioning. We studied this phenomenon in Sprague-Dawley rats by pairing a vibrotactile conditioned stimulus (CS) with a tailshock unconditioned stimulus (US). Experiment 1 showed that spinal rats exhibit differential conditioning, having longer tail-flick latencies on the tail-flick test during a CS that was paired with the US (conditioned antinociception). Experiment 2 showed that… 
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References

SHOWING 1-10 OF 24 REFERENCES
Classical conditioning, sensitization and habituation in the spinal cat
  • R. Durkovic
  • Psychology, Biology
    Physiology & Behavior
  • 1975
Associative learning and memory for an antinociceptive response in the spinalized rat.
TLDR
The present experiments suggest that the circuitry needed to obtain associative and memorylike effects is present within the spinal cord.
Classical conditioning of the hindlimb flexion reflex in the acute spinal cat
Acute spinal cats were prepared by partial decerebration and spinal section using ether. Animals were given training (hindlimb flexor muscle reflex response) in a classical conditioning situation
Classical conditioning with auditory discrimination of the eye blink in decerebrate cats.
TLDR
The results support the notion that the brainstem reticular formation can support a conditioned response which isbehaviorally similar to that obtained in the intact animal.
Activation of the opioid and nonopioid hypoalgesic systems at the level of the brainstem and spinal cord: does a coulometric relation predict the emergence or form of environmentally induced hypoalgesia?
TLDR
It is found that a coulometric relation does not predict either the emergence or the form of shock-induced hypoalgesia in decerebrate rats, and no evidence was obtained that the brainstem's opioid hypOalgesic system can be activated by ascending neurons.
Hilgard and Marquis' Conditioning and learning
, 4 , induced hypoalgesia ?
  • Behavioral Neuroscience
  • 1993
Memory traces in spinal cord
Role of sumoval of neocortex
  • Journal of Comparative and Physiologipraspinal systems in environmentally induced antinocicepcal Psychology
  • 1990
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