Evidence for NK cell subsets based on chemokine receptor expression.

  title={Evidence for NK cell subsets based on chemokine receptor expression.},
  author={Robert D. Berahovich and Nu L. Lai and Zheng Wei and Lewis L. Lanier and Thomas J. Schall},
  journal={Journal of immunology},
  volume={177 11},
To help understand the role of chemokines in NK cell trafficking, we determined the chemokine receptor profiles of three different human NK cell lines and freshly isolated primary human NK cells. The cell lines overlapped in their chemokine receptor profiles: CXCR3 and CXCR4 were expressed by all three lines, whereas CCR1, CCR4, CCR6, CCR7, and CX3CR1 were expressed by only one or two of the lines, and no other chemokine receptors were detected. Freshly isolated primary NK cells were found to… CONTINUE READING

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