Evidence for Linkage between Hl-a Histocompatibility Genes and Those Involved in the Synthesis of the Second Component of Complement

Abstract

HL-A analysis of a family with C2 deficiency revealed evidence for close linkage between the C2 defect and the histocompatibility HL-A loci. The propositus was homozygous both for C2 deficiency and the HL-A haplotype 10,W18. Among seven children of three double backcross matings, no recombinants were found. The possible significance of such linkage is… (More)

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Cite this paper

@article{Fu1974EvidenceFL, title={Evidence for Linkage between Hl-a Histocompatibility Genes and Those Involved in the Synthesis of the Second Component of Complement}, author={S. M. Fu and Hanna Kunkel and H. P. Brusman and Frederick Allen and Marilena Fotino}, journal={The Journal of Experimental Medicine}, year={1974}, volume={140}, pages={1108 - 1111} }