Evidence for Hoogsteen GC base pairs in the proton-induced transition from right-handed to left-handed poly(dG-dC).poly(dG-dC).

Abstract

The structure of double-helical poly(dG-dC).poly(dG-dC) is investigated at various pH values with Raman spectroscopy, absorption spectroscopy, and circular dichroism. A comparison is made between the B-form with Watson-Crick base pairing at 1 mM [Na+] and pH 7.2, the Z-form with Watson-Crick base pairing at 4 M [Na+] and pH 7.2, and a different structure at… (More)

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@article{SegersNolten1997EvidenceFH, title={Evidence for Hoogsteen GC base pairs in the proton-induced transition from right-handed to left-handed poly(dG-dC).poly(dG-dC).}, author={G. M. J. Segers-Nolten and Nanna M. Sijtsema and C. Stephan - Otto}, journal={Biochemistry}, year={1997}, volume={36 43}, pages={13241-7} }