Evidence for DNA loss as a determinant of genome size.

@article{Petrov2000EvidenceFD,
  title={Evidence for DNA loss as a determinant of genome size.},
  author={Dmitri A. Petrov and Todd A. Sangster and J. Spencer Johnston and Daniel L. Hartl and Kerry L Shaw},
  journal={Science},
  year={2000},
  volume={287 5455},
  pages={
          1060-2
        }
}
  • Dmitri A. Petrov, Todd A. Sangster, +2 authors Kerry L Shaw
  • Published 2000
  • Biology, Medicine
  • Science
  • Eukaryotic genome sizes range over five orders of magnitude. This variation cannot be explained by differences in organismic complexity (the C value paradox). To test the hypothesis that some variation in genome size can be attributed to differences in the patterns of insertion and deletion (indel) mutations among organisms, this study examines the indel spectrum in Laupala crickets, which have a genome size 11 times larger than that of Drosophila. Consistent with the hypothesis, DNA loss is… CONTINUE READING

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    References

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    SHOWING 1-10 OF 12 REFERENCES

    Annu. Rev. Biochem. Proc. R. Soc. London, Ser. B

    • A M Weiner, P L Deininger, A Efstratiadis
    • Annu. Rev. Biochem. Proc. R. Soc. London, Ser. B
    • 1986

    Annu. Rev. Genet

    • C A Thomas
    • Annu. Rev. Genet
    • 1971

    Gen. Physiol

    • A E Mirsky, H Ris
    • Gen. Physiol
    • 1951

    J. Mol. Evol

    • M Sharp, W.-H Li
    • J. Mol. Evol
    • 1989

    Mol. Biol. Evol

    • D A Petrov, Y.-C Chao, E C Stephenson, D L Hartl
    • Mol. Biol. Evol
    • 1998

    Mol. Biol. Evol

    • D A Petrov, D L Hartl
    • Mol. Biol. Evol
    • 1998

    Mol. Biol. Evol. Nature

    • H Ogata, W Fujibuchi, M Kanehisa, Febs Lett
    • Mol. Biol. Evol. Nature
    • 1995

    Supported by National Science Foundation grant DEB-9729325 to K.L.S., National Institutes of Health grants to

    • Supported by National Science Foundation grant DEB-9729325 to K.L.S., National Institutes of Health grants to