Evidence for CALM in directing VAMP2 trafficking.

@article{Harel2008EvidenceFC,
  title={Evidence for CALM in directing VAMP2 trafficking.},
  author={Asaff Harel and Fangbai Wu and Mark P. Mattson and Christa M Morris and Pamela J Yao},
  journal={Traffic},
  year={2008},
  volume={9 3},
  pages={417-29}
}
Clathrin assembly lymphoid myeloid leukemia protein (CALM) is a clathrin assembly protein with a domain structure similar to the neuron-specific assembly protein AP180. We have previously found that CALM is expressed in neurons and present in synapses. We now report that CALM has a neuron-related function: it facilitates the endocytosis of the synaptic vesicle protein VAMP2 from the plasma membrane. Overexpression of CALM leads to the reduction of cell surface VAMP2, whereas knockdown of CALM… CONTINUE READING

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