Evidence for CALM in directing VAMP2 trafficking.

  title={Evidence for CALM in directing VAMP2 trafficking.},
  author={Asaff Harel and Fangbai Wu and Mark P. Mattson and Christa M Morris and Pamela J Yao},
  volume={9 3},
Clathrin assembly lymphoid myeloid leukemia protein (CALM) is a clathrin assembly protein with a domain structure similar to the neuron-specific assembly protein AP180. We have previously found that CALM is expressed in neurons and present in synapses. We now report that CALM has a neuron-related function: it facilitates the endocytosis of the synaptic vesicle protein VAMP2 from the plasma membrane. Overexpression of CALM leads to the reduction of cell surface VAMP2, whereas knockdown of CALM… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 69 extracted citations


Publications referenced by this paper.
Showing 1-10 of 44 references

Similar Papers

Loading similar papers…