Evidence for 21-aminosteroid association with the hydrophobic domains of brain microvessel endothelial cells.

@article{Audus1991EvidenceF2,
  title={Evidence for 21-aminosteroid association with the hydrophobic domains of brain microvessel endothelial cells.},
  author={Kenneth L. Audus and François L. Guillot and J M Braughler},
  journal={Free radical biology & medicine},
  year={1991},
  volume={11 4},
  pages={361-71}
}
Studies were conducted to demonstrate 21-aminosteroid distribution into the hydrophobic or lipid domains of biological membranes, a presumed site at which these compounds inhibit lipid peroxidation. Bovine brain microvessel endothelial cells (BMECs) were labeled with diphenylhexatriene fluorophores and interactions with cell membranes characterized with… CONTINUE READING