Evidence-based organ-sparing radiotherapy in head and neck cancer.

  title={Evidence-based organ-sparing radiotherapy in head and neck cancer.},
  author={Piet Dirix and Sandra Nuyts},
  journal={The Lancet. Oncology},
  volume={11 1},
Intensification of radiotherapy treatment for locally advanced head and neck cancer by use of altered fractionation schedules or concomitant chemotherapy has resulted in substantially improved locoregional control and survival. However, these improvements have come at the cost of increased acute, and late, toxic effects. The application of technological advances, such as intensity-modulated radiotherapy, is expected to further improve the therapeutic index of radiotherapy for head and neck… CONTINUE READING


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