Evidence-based medicine was bound to fail: a report to Alvan Feinstein.

@article{Fava2017EvidencebasedMW,
  title={Evidence-based medicine was bound to fail: a report to Alvan Feinstein.},
  author={Giovanni Andrea Fava},
  journal={Journal of clinical epidemiology},
  year={2017},
  volume={84},
  pages={3-7}
}
John Ioannidis has provided a lucid account, in the form of a report to David Sackett, of how evidence-based medicine (EBM) was hijacked to serve vested interests: major randomized controlled trials are largely done by and for the benefit of the industry; meta-analyses and guidelines are flooded with conflicts of interest; national and federal research funds are unable to address basic clinical questions. Nonetheless, EBM would remain a worthwhile goal. In this paper, in the form of a report to… CONTINUE READING
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