Evidence-based Emergency Medicine/Critically Appraised Topic. The efficacy of recombinant activated factor VII in severe trauma.

STUDY OBJECTIVE The use of recombinant activated factor VII (rFVIIa) in severe trauma is controversial. This evidence-based emergency medicine review evaluates the existing evidence about the efficacy and safety of rFVIIa for the management of severe trauma. METHODS We searched MEDLINE, EMBASE, the Cochrane Library, and other databases. We limited our… CONTINUE READING