• Corpus ID: 3762271

Evidence and Arrive Assessment on Neuroprotective Effects of Flavonols Quercetin , Rutin and Isoquercitrin in Neurodegenerative Diseases ’ Models

  title={Evidence and Arrive Assessment on Neuroprotective Effects of Flavonols Quercetin , Rutin and Isoquercitrin in Neurodegenerative Diseases ’ Models},
  author={A. C. Duarte and Maycon Giovani Santanai and Gulhermedi Camilo Orfalii and Carlos Tadeu Parisi de Oliveira and Denise Gonçalves Priolli and S{\~a}o Francisco},
This paper was based on a literature search of PubMed and Scielo databases using the keywords “Flavonoids, Neuroprotection, Quercetin, Rutin, Isoquercitrin, Alzheimer, Parkinson, Huntington” and combinations of all the words. We collected relevant publications, during the period of 2000 to 2016, emphasizing in vivo and in vitro studies with neurological assessment of flavonol’s potentials, as well as classifying studies according to evidence levels, in order to elucidate evidence-based… 

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Literature Evidence and ARRIVE Assessment on Neuroprotective Effects of Flavonols in Neurodegenerative Diseases' Models.

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Several studies in vitro, in experimental animals and in humans, have provided supportive evidence for neuroprotective effects of quercetin, either against neurotoxic chemicals or in various models of neuronal injury and neurodegenerative diseases.

Neuroprotective Role of Natural Polyphenols.

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Review of anticancer mechanisms of isoquercitin.

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