Evidence against potassium as an endothelium-derived hyperpolarizing factor in rat mesenteric small arteries.

@article{Lacy2000EvidenceAP,
  title={Evidence against potassium as an endothelium-derived hyperpolarizing factor in rat mesenteric small arteries.},
  author={Peter S Lacy and Guy R. Pilkington and Rajesh Hanvesakul and Heather Fish and John P Boyle and Herbert Thurston},
  journal={British journal of pharmacology},
  year={2000},
  volume={129 3},
  pages={605-11}
}
1. Endothelium-derived hyperpolarizing factor (EDHF) has recently been identified as potassium released from endothelial cells into the myo-endothelial space. The present study was designed to test this hypothesis. 2. In rat small mesenteric arteries, mounted in a wire myograph, relaxation to acetylcholine or potassium was not significantly changed following incubation with oxadiazolo-quinoxalin-1-one (ODQ, 4 microM) and indomethacin (10 microM, n = 9). 3. Maximal relaxations to acetylcholine… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

Similar Papers

Loading similar papers…