Evidence against DNA polymerase β as a candidate gene for Werner syndrome

Abstract

Werner syndrome (WS) is a rare autosomal recessive disorder of humans characterized by the premature onset and accelerated rate of development of several major age-related disorders. An aberration in DNA replication or repair is suggested by the evidence of genome instability. Since the structural gene for DNA polymerase β maps within the region of the WS… (More)
DOI: 10.1007/BF00202813

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