Evidence That Kidney Function but Not Type 2 Diabetes Determines Retinol-Binding Protein 4 Serum Levels

@article{Henze2008EvidenceTK,
  title={Evidence That Kidney Function but Not Type 2 Diabetes Determines Retinol-Binding Protein 4 Serum Levels},
  author={Andrea Henze and Simone K. Frey and Jens Raila and Martin Tepel and Alexandra Scholze and Andreas F. H. Pfeiffer and M. Weickert and Joachim Spranger and Florian J. Schweigert},
  journal={Diabetes},
  year={2008},
  volume={57},
  pages={3323 - 3326}
}
OBJECTIVE It has been suggested that retinol-binding protein 4 (RBP4) links adiposity, insulin resistance, and type 2 diabetes. However, circulating RBP4 levels are also affected by kidney function. Therefore, the aim of this study was to test whether RBP4 serum levels are primarily associated with kidney function or type 2 diabetes. RESEARCH DESIGN AND METHODS RBP4 serum concentration was determined by enzyme-linked immunosorbent assay in 126 nondiabetic and 104 type 2 diabetic subjects. The… CONTINUE READING
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