Evidence That Breast Tissue Stiffness Is Associated with Risk of Breast Cancer

@inproceedings{Boyd2014EvidenceTB,
  title={Evidence That Breast Tissue Stiffness Is Associated with Risk of Breast Cancer},
  author={Norman F. Boyd and Qing Li and Olga Melnichouk and Ella Huszti and Lisa J Martin and Anoma Gunasekara and Gord E Mawdsley and Martin Joel Yaffe and Salomon Minkin},
  booktitle={PloS one},
  year={2014}
}
BACKGROUND Evidence from animal models shows that tissue stiffness increases the invasion and progression of cancers, including mammary cancer. We here use measurements of the volume and the projected area of the compressed breast during mammography to derive estimates of breast tissue stiffness and examine the relationship of stiffness to risk of breast cancer. METHODS Mammograms were used to measure the volume and projected areas of total and radiologically dense breast tissue in the… CONTINUE READING
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