EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli.

@article{Nishino2002EvgAOT,
  title={EvgA of the two-component signal transduction system modulates production of the yhiUV multidrug transporter in Escherichia coli.},
  author={Kunihiko Nishino and Akihito Yamaguchi},
  journal={Journal of bacteriology},
  year={2002},
  volume={184 8},
  pages={
          2319-23
        }
}
Overexpression of the EvgA regulator of the two-component signal transduction system was previously found to modulate multidrug resistance of Escherichia coli by increasing efflux of drugs (K. Nishino and A. Yamaguchi, J. Bacteriol. 183:1455-1458, 2001). Here we present data showing that EvgA contributes to multidrug resistance through increased expression of the multidrug transporter yhiUV gene. 
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