Every silver lining has a cloud: the scientific and animal welfare issues surrounding a new approach to the production of transgenic animals.

Abstract

The scientific basis and advantages of using recently developed CRISPR/Cas-9 technology for transgenesis have been assessed with respect to other production methods, laboratory animal welfare, and the scientific relevance of transgenic models of human diseases in general. As the new technology is straightforward, causes targeted DNA double strand breaks and… (More)

Topics

Cite this paper

@article{Combes2014EverySL, title={Every silver lining has a cloud: the scientific and animal welfare issues surrounding a new approach to the production of transgenic animals.}, author={Robert David Combes and Michael Balls}, journal={Alternatives to laboratory animals : ATLA}, year={2014}, volume={42 2}, pages={137-45} }