Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients.

@article{Sheshgiri2009EverolimusBN,
  title={Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients.},
  author={Rohit Sheshgiri and Finn Gustafsson and Jill Sheedy and Vivek Rao and Heather J. Ross and Diego Hern{\'a}n Delgado},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  year={2009},
  volume={28 11},
  pages={1193-7}
}
BACKGROUND Human leukocyte antigen-G (HLA-G), a protein primarily expressed during pregnancy, helps maintain maternal-fetal immune tolerance. Myocardial and/or soluble HLA-G (sHLA-G) expression confers protection against rejection and vasculopathy after heart transplantation. Although the precise mechanisms remain unclear, immunosuppressive therapy has been reported to influence this expression. METHODS We compared sHLA-G expression in heart transplant recipients receiving two different anti… CONTINUE READING
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