Everolimus: side effect profile and management of toxicities in breast cancer

@article{Paplomata2013EverolimusSE,
  title={Everolimus: side effect profile and management of toxicities in breast cancer},
  author={Elisavet Paplomata and Amelia B. Zelnak and Ruth M. O’Regan},
  journal={Breast Cancer Research and Treatment},
  year={2013},
  volume={140},
  pages={453-462}
}
Everolimus is an orally available inhibitor of the mammalian target of rapamycin (mTOR), which has been approved in combination with exemestane for hormone receptor-positive (HR) breast cancer after failure of treatment with non-steroidal aromatase inhibitors. Everolimus is generally very well tolerated with most common side effects including stomatitis, rash, fatigue, hyperglycemia, hyperlipidemia, and myelosuppression. Most of these side effects are mild and resolve with dose interruptions or… CONTINUE READING

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