Events that regulate differentiation of alpha beta TCR+ and gamma delta TCR+ T cells from a common precursor.

Abstract

T cells in vertebrates are composed of two distinct lineages of cells distinguished by the type of antigen receptors they express: the conventional population expresses TCR composed of alpha beta heterodimers while a smaller fraction of mature T cells displays gamma delta TCRs on the cell surface. The alpha beta and gamma delta T cells develop from common T… (More)

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