Events in degenerating cat peripheral nerve: induction of Schwann cell S phase and its relation to nerve fibre degeneration.

@article{Pellegrino1986EventsID,
  title={Events in degenerating cat peripheral nerve: induction of Schwann cell S phase and its relation to nerve fibre degeneration.},
  author={R G Pellegrino and Manolis Politis and Jennifer M. Ritchie and Peter S. Spencer},
  journal={Journal of neurocytology},
  year={1986},
  volume={15 1},
  pages={17-28}
}
Severance of a peripheral nerve leads to a characteristic series of events in the distal stump, including the dissolution of axons and myelin and the proliferation of Schwann cells within their basal lamina. This study examines the relationship between the spatial-temporal pattern of the induction of the Schwann cell S phase, loss of the structural and functional properties of axolemma, and the clearance of myelin debris in the cat tibial nerve. Nerve transection stimulated a monophasic… CONTINUE READING