Event-Related Functional MRI Study on Central Representation of Acute Muscle Pain Induced by Electrical Stimulation

@article{Niddam2002EventRelatedFM,
  title={Event-Related Functional MRI Study on Central Representation of Acute Muscle Pain Induced by Electrical Stimulation},
  author={David M. Niddam and T. C. Yeh and Yu-Te Wu and Po-Lei Lee and L. T. Ho and Lars Arendt-Nielsen and Andrew C. N. Chen and J. C. Hsieh},
  journal={NeuroImage},
  year={2002},
  volume={17},
  pages={1437-1450}
}
Although pathological muscle pain involves a significantly larger population than any other pain condition, the central mechanisms are less explored than those of cutaneous pain. The aims of the study were to establish the pain matrix for muscle pain in the full head volume and, further, to explore the possibility of a functional segregation to nonpainful and painful stimuli within the area of the parasylvian cortex corresponding to the secondary somatosensory area. Additionally, we speculate… 
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References

SHOWING 1-10 OF 97 REFERENCES
Functional MR imaging analysis of pain-related brain activation after acute mechanical stimulation.
TLDR
The interindividual variability found in this functional MR imaging study calls for repetitive single-subject analysis or more extensive studies of large groups of patients, based on fMR imaging analysis of brain activation after tonic mechanically induced pain.
Central representation of chronic ongoing neuropathic pain studied by positron emission tomography
Expectation of Pain Enhances Responses to Nonpainful Somatosensory Stimulation in the Anterior Cingulate Cortex and Parietal Operculum/Posterior Insula: an Event-Related Functional Magnetic Resonance Imaging Study
TLDR
It is suggested that ACC and PO/PI are involved in modulation of affective aspect of sensory perception by the uncertain expectation of painful stimulus.
Functional MRI study of thalamic and cortical activations evoked by cutaneous heat, cold, and tactile stimuli.
TLDR
Functional magnetic resonance imaging is used to locate discrete regions of the thalamus, insula, and second somatosensory cortex modulated during innocuous and noxious thermal stimulation and provides support for a role of the anterior insula and S2 in the perception of pain; whereas the posterior insula appears to be involved in tactile and innocuous temperature perception.
Pain intensity processing within the human brain: a bilateral, distributed mechanism.
TLDR
Results confirm the existence of a highly distributed, bilateral supraspinal mechanism engaged in the processing of pain intensity and conserve pain intensity information across multiple, functionally distinct brain areas.
Central processing of rectal pain: a functional MR imaging study.
TLDR
The activation patterns observed in this study support the hypothesis that the cerebral processing of visceral pain involves multiple components, similar to the central processing of somatic pain.
A Comparative fMRI Study of Cortical Representations for Thermal Painful, Vibrotactile, and Motor Performance Tasks
TLDR
The study indicates that fMRI enables examination of cortical networks subserving pain perception at an anatomical detail not available with other brain imaging techniques and shows that this cortical network underlying pain perception shares components with the networks underlying touch perception and motor execution.
Non-painful and painful stimulation of human skin and muscle: analysis of cerebral evoked potentials.
Cortical representation of pain: functional characterization of nociceptive areas near the lateral sulcus
Functional MRI of pain- and attention-related activations in the human cingulate cortex.
TLDR
Evidence is provided for a region in the posterior part of the ACC that is involved in pain and a more anterior region involved in other attention-demanding cognitive tasks, which shed light on pain- and attention-related cognitive processes.
...
...