Event-Related Functional MRI Study on Central Representation of Acute Muscle Pain Induced by Electrical Stimulation

  title={Event-Related Functional MRI Study on Central Representation of Acute Muscle Pain Induced by Electrical Stimulation},
  author={David M. Niddam and T. C. Yeh and Yu-Te Wu and Po-Lei Lee and L. T. Ho and Lars Arendt-Nielsen and Andrew C. N. Chen and J. C. Hsieh},
Although pathological muscle pain involves a significantly larger population than any other pain condition, the central mechanisms are less explored than those of cutaneous pain. The aims of the study were to establish the pain matrix for muscle pain in the full head volume and, further, to explore the possibility of a functional segregation to nonpainful and painful stimuli within the area of the parasylvian cortex corresponding to the secondary somatosensory area. Additionally, we speculate… 

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