Corpus ID: 9259372

Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain.

@article{Graham1993EvennumberedRC,
  title={Even-numbered rhombomeres control the apoptotic elimination of neural crest cells from odd-numbered rhombomeres in the chick hindbrain.},
  author={A. Graham and I. Heyman and A. Lumsden},
  journal={Development},
  year={1993},
  volume={119 1},
  pages={
          233-45
        }
}
  • A. Graham, I. Heyman, A. Lumsden
  • Published 1993
  • Biology, Medicine
  • Development
  • Neural crest cells originate at three discontinuous levels along the rostrocaudal axis of the chick rhombencephalon, centred on rhombomeres 1 and 2, 4 and 6, respectively. These are separated by the odd-numbered rhombomeres r3 and r5 which are depleted of migratory neural crest cells. Here we show elevated levels of apoptosis in the dorsal midline of r3 and r5, immediately following the formation of these rhombomeres at the developmental stage (10-12) when neural crest cells would be expected… CONTINUE READING
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