Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses.

@article{Suthar2009EvasionAD,
  title={Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses.},
  author={Mehul S Suthar and Michael Gale and David M. Owen},
  journal={Cellular microbiology},
  year={2009},
  volume={11 6},
  pages={880-8}
}
Signalling pathways leading to type I interferon production are the first line of defence employed by the host to combat viruses, and represent a barrier that an invading virus must overcome in order to establish infection. In this review we highlight the ability of two members of the Flaviviridae, a globally distributed family of RNA viruses that represent a significant public health concern, to disrupt and evade these defences. Hepatitis C virus is a hepatotropic virus, infecting greater than… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 15 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 84 references

Acute hepatitis C

View 4 Excerpts
Highly Influenced

Hepatitis C virus infection.

The New England journal of medicine • 2001
View 4 Excerpts
Highly Influenced

Origin of the West Nile virus responsible for an outbreak of encephalitis in the north - eastern United States

R. S. Lanciotti, G. D. Ebel, V. Deubel, A. J. Kerst
Science • 1999
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…