Evaluation of white matter damage in patients with Alzheimer’s disease and in patients with mild cognitive impairment by using diffusion tensor imaging

@article{Ukmar2008EvaluationOW,
  title={Evaluation of white matter damage in patients with Alzheimer’s disease and in patients with mild cognitive impairment by using diffusion tensor imaging},
  author={Maja Ukmar and Elisa Makuc and Maria Luisa Onor and Gabrielle Garbin and Marianna Trevisiol and Maria Assunta Cova},
  journal={La radiologia medica},
  year={2008},
  volume={113},
  pages={915-922}
}
The objective of this study was to evaluate white matter tissue damage in patients with Alzheimer’s disease (AD) and in patients with mild cognitive impairment (MCI) using diffusion tensor imaging (DTI). Forty-seven subjects were evaluated: 14 patients with AD, 15 with MCI and 18 healthy volunteers. All subjects were studied using conventional magnetic resonance imaging (MRI) and DTI (32 directions) with a 1.5 T magnet. Fractional anisotropy (FA) was measured in the following regions: frontal… CONTINUE READING

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