Evaluation of tumor shape variability in head-and-neck cancer patients over the course of radiation therapy using implanted gold markers.

@article{HammingVrieze2012EvaluationOT,
  title={Evaluation of tumor shape variability in head-and-neck cancer patients over the course of radiation therapy using implanted gold markers.},
  author={Olga Hamming-Vrieze and Simon R. van Kranen and Suzanne van Beek and Wilma D Heemsbergen and Marcel B van Herk and Michiel Wilhelmus Maria van den Brekel and J. Sonke and C R N Rasch},
  journal={International journal of radiation oncology, biology, physics},
  year={2012},
  volume={84 2},
  pages={
          e201-7
        }
}
PURPOSE This study quantifies tumor shape variability in head-and-neck cancer patients during radiation therapy using implanted markers. METHODS AND MATERIALS Twenty-seven patients with oropharyngeal tumors treated with (chemo)radiation were included. Helical gold markers (0.35 × 2 mm, 3-10/patient, average 6) were implanted around the tumor. Markers were identified on planning computed tomography (CT) and daily cone beam CT (CBCT). After bony anatomy registration, the daily vector length on… CONTINUE READING

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