Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway.

@article{Ritala2014EvaluationOT,
  title={Evaluation of tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots for the production of geraniol, the first committed step in terpenoid indole alkaloid pathway.},
  author={A. Ritala and Lemeng Dong and Nicole Imseng and T. Sepp{\"a}nen-Laakso and N. Vasil'ev and S. van der Krol and H. Rischer and Hannu Maaheimo and Arho Virkki and J. Br{\"a}ndli and S. Schillberg and R. Eibl and H. Bouwmeester and K. Oksman-Caldentey},
  journal={Journal of biotechnology},
  year={2014},
  volume={176},
  pages={
          20-8
        }
}
  • A. Ritala, Lemeng Dong, +11 authors K. Oksman-Caldentey
  • Published 2014
  • Biology, Medicine
  • Journal of biotechnology
  • The terpenoid indole alkaloids are one of the major classes of plant-derived natural products and are well known for their many applications in the pharmaceutical, fragrance and cosmetics industries. Hairy root cultures are useful for the production of plant secondary metabolites because of their genetic and biochemical stability and their rapid growth in hormone-free media. Tobacco (Nicotiana tabacum L. cv. Petit Havana SR1) hairy roots, which do not produce geraniol naturally, were engineered… CONTINUE READING
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    References

    SHOWING 1-10 OF 46 REFERENCES
    Functional characterisation of genes involved in pyridine alkaloid biosynthesis in tobacco.
    • 47
    Agrobacterium rhizogenes-mediated transformation: root cultures as a source of alkaloids.
    • 259
    • PDF