Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection.

@article{Tebas2004EvaluationOT,
  title={Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection.},
  author={Pablo Tebas and Kevin H Yarasheski and Keith Henry and Sherri Claxton and Erin M. Kane and B Bordenave and Michael K. Klebert and William G. Powderly},
  journal={AIDS research and human retroviruses},
  year={2004},
  volume={20 6},
  pages={589-94}
}
In spite of indisputable benefits, the use of antiretroviral therapy is associated with multiple metabolic complications. Switching to simpler regimens might maintain viral suppression, improve metabolic side effects, and provide insight into the pathogenesis of these complications. Our objective was to carefully characterize the virological and metabolic effects of switching from a successful protease inhibitor (PI)-based antiretroviral regimen to a nonnucleoside reverse transcriptase… CONTINUE READING
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