Evaluation of the toxicity of subretinal triamcinolone acetonide in the rabbit.

@article{Kozak2006EvaluationOT,
  title={Evaluation of the toxicity of subretinal triamcinolone acetonide in the rabbit.},
  author={Igor Kozak and Lingyun Cheng and Tim Mendez and Marie C. Davidson and William R. Freeman},
  journal={Retina},
  year={2006},
  volume={26 7},
  pages={811-7}
}
PURPOSE Subretinal triamcinolone acetonide (TCA) might be a useful adjuvant in the treatment of subretinal neovascularization. The purpose of this study was to test the toxicity of subretinal TCA in the rabbit eye. METHODS Sixteen New Zealand rabbits were vitrectomized and injected with either decanted TCA solution or vehicle. The concentration of injected TCA was 2 mg, and the delivered volume was 10 microL. Rabbits were examined on days 1, 3, and 7 and then once a week up to 3 months after… CONTINUE READING