Evaluation of the roles of the Leiden V mutation and ACE I/D polymorphism in subtypes of ischaemic stroke

@article{Szolnoki2001EvaluationOT,
  title={Evaluation of the roles of the Leiden V mutation and ACE I/D polymorphism in subtypes of ischaemic stroke},
  author={Zolt{\'a}n Szolnoki and Ferenc Somogyv{\'a}ri and Andr{\'a}s Kondacs and Mihaly Szabo and Lajos Fodor},
  journal={Journal of Neurology},
  year={2001},
  volume={248},
  pages={756-761}
}
Objective The Leiden V mutation, which causes activated protein C resistance and thrombophilia, has been found to be a risk factor for venous thrombosis. The angiotensin converting enzyme (ACE) D allele indirectly exerts an unfavourable effect on the vasoregulatory system. In this study, the frequency of these mutations was analysed in different subtypes of ischaemic stroke. Method and material According to the clinical and radiological features 664 Hungarian patients who had suffered acute… CONTINUE READING
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