Evaluation of the roles of common genetic mutations in leukoaraiosis.

  title={Evaluation of the roles of common genetic mutations in leukoaraiosis.},
  author={Zolt{\'a}n Szolnoki and Ferenc Somogyv{\'a}ri and Andr{\'a}s Kondacs and Mihaly Szabo and Lajos Fodor},
  journal={Acta neurologica Scandinavica},
  volume={104 5},
OBJECTIVES Leukoaraiosis, a relatively frequent neuroimaging entity, is presumed to be primarily a vascular problem. However, it can be explained only in part by vascular risk factors. With the assumption of genetic susceptibility, the roles of common genetic polymorphisms and mutations in leukoaraiosis were examined in this study. MATERIAL AND METHODS A detailed clinical scrutiny of 843 Hungarian neurological patients with mild cognitive-like complaints revealed 229 subjects with… CONTINUE READING


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