Evaluation of the relationship between inducible nitric oxide synthase (iNOS) activity and effects of melatonin in experimental osteoporosis in the rat

Abstract

Inducible nitric oxide synthase (iNOS) plays a critical role in the pathogenesis of osteoporosis. iNOS generates nitric oxide (NO), a free radical contributing to the imbalance between bone formation and resorption caused by estrogen depletion. Melatonin is the major product of the pineal gland which is known to diminish iNOS expression and NO production… (More)
DOI: 10.1007/s00276-005-0065-9

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@article{Oktem2005EvaluationOT, title={Evaluation of the relationship between inducible nitric oxide synthase (iNOS) activity and effects of melatonin in experimental osteoporosis in the rat}, author={Gulperi Oktem and Sercan Uslu and Seda H. Vatansever and Huseyin Aktug and M. E. Yurtseven and A. Karasu Uysal}, journal={Surgical and Radiologic Anatomy}, year={2005}, volume={28}, pages={157-162} }