Evaluation of the protective efficacy of a newly identified immunogenic protein, HP0272, of Streptococcus suis.

@article{Chen2010EvaluationOT,
  title={Evaluation of the protective efficacy of a newly identified immunogenic protein, HP0272, of Streptococcus suis.},
  author={Bo Chen and Anding Zhang and Ran Li and Xiaofeng Mu and Hongkui He and Huanchun Chen and Meilin Jin},
  journal={FEMS microbiology letters},
  year={2010},
  volume={307 1},
  pages={12-8}
}
Streptococcus suis serotype 2 (SS2) infection is a major cause of sudden death in pigs and is of concern for humans as it has strong zoonotic capabilities. Developing novel effective vaccines would be beneficial to control SS2 infection. HP0272 is a novel immunogenic surface protein; its protective efficacy remains to be evaluated. The present mouse model found that the purified recombinant HP0272 could elicit a significant humoral antibody response, and to confer complete protection against a… CONTINUE READING

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