Evaluation of the mutagenicity and carcinogenicity of motor vehicle emissions in short-term bioassays.

@article{Lewtas1983EvaluationOT,
  title={Evaluation of the mutagenicity and carcinogenicity of motor vehicle emissions in short-term bioassays.},
  author={Joellen Lewtas},
  journal={Environmental Health Perspectives},
  year={1983},
  volume={47},
  pages={141 - 152}
}
Incomplete combustion of fuel in motor vehicles results in the emission of submicron carbonaceous particles which, after cooling and dilution, contain varying quantities of extractable organic constituents. These organics are mutagenic in bacteria. Confirmatory bioassays in mammalian cells provide the capability of detecting chromosomal and DNA damage in addition to gene mutations. In order to evaluate the mutagenicity of these organics in mammalian cells, extractable organics from particle… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 27 CITATIONS

Genotoxicity of motorcycle exhaust particles in vivo and in vitro.

  • Toxicological sciences : an official journal of the Society of Toxicology
  • 2004
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 38 REFERENCES

Skin carcinogenesis studies of emission extracts.

  • Developments in toxicology and environmental science
  • 1982

Evaluation of Mutagenic Effects of Diesel Emissions I . Tests for Heritable and Germcell Effects in the Mouse

L. B. Russell, W. M. Generoso, W. L. Russell, E. F. Oakberg
  • 1981