Evaluation of the motor initiation hypothesis of APD-induced conditioned avoidance decreases

@article{Li2004EvaluationOT,
  title={Evaluation of the motor initiation hypothesis of APD-induced conditioned avoidance decreases},
  author={Ming Li and Jun Parkes and Paul N. Fletcher and Shitij Kapur},
  journal={Pharmacology Biochemistry and Behavior},
  year={2004},
  volume={78},
  pages={811-819}
}
Antipsychotic drugs (APDs) selectively disrupt conditioned avoidance responding (CAR)--a feature that distinguishes them from all other psychotropics. It is thought that this effect reflects their effect on motor initiation; however, this conclusion is questionable because most studies it relies on have often examined avoidance responding under APD treatment, and tested animals with preshock stimuli followed by the footshock. APD-induced CAR effects are confounded by APDs' motor effects and by… CONTINUE READING
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