Evaluation of the influence of tissue parasite density on hematological and phenotypic cellular parameters of circulating leukocytes and splenocytes during ongoing canine visceral leishmaniasis

@article{Guerra2008EvaluationOT,
  title={Evaluation of the influence of tissue parasite density on hematological and phenotypic cellular parameters of circulating leukocytes and splenocytes during ongoing canine visceral leishmaniasis},
  author={Luanda Liboreiro Guerra and Andr{\'e}a Teixeira-Carvalho and Rodolfo Cordeiro Giunchetti and Olindo Assis Martins-Filho and Alexandre Barbosa Reis and Rodrigo Corr{\^e}a-Oliveira},
  journal={Parasitology Research},
  year={2008},
  volume={104},
  pages={611-622}
}
During Leishmania infection, tissue parasitism at different sites may differ and imply distinct immunopathological patterns during canine visceral leishmaniasis (CVL). For this reason, we have assessed by flow cytometry the impact of spleen and skin parasite density on the phenotypic profile of splenocytes and circulating leukocytes of 40 Brazilian dogs naturally infected by Leishmania chagasi categorized according to splenic and cutaneous parasite load. Our major statistically significant… CONTINUE READING

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