Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites.

@article{Aboulaila2010EvaluationOT,
  title={Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites.},
  author={Mahmoud Aboulaila and Kazuya Nakamura and Yadav Govind and Naoaki Yokoyama and Ikuo Igarashi},
  journal={Veterinary parasitology},
  year={2010},
  volume={167 1},
  pages={19-27}
}
Epoxomicin potently and irreversibly inhibits the catalytic activity of proteasomal subunits. Treatment of proliferating cells with epoxomicin results in cell death through accumulation of ubiquinated proteins. Thus, epoxomicin has been proposed as a potential anti-cancer drug. In the present study, the inhibitory effects of epoxomicin on the in vitro growth of bovine and equine Babesia parasites were evaluated. The inhibitory effect of epoxomicin on the in vivo growth of Babesia microti was… CONTINUE READING

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