Evaluation of the immunofluorescent antibody test for the diagnosis of human leptospirosis.

@article{Appassakij1995EvaluationOT,
  title={Evaluation of the immunofluorescent antibody test for the diagnosis of human leptospirosis.},
  author={Hatsadee Appassakij and Khachornsakdi Silpapojakul and R Wansit and J Woodtayakorn},
  journal={The American journal of tropical medicine and hygiene},
  year={1995},
  volume={52 4},
  pages={340-3}
}
Sera from 175 patients with clinically suspected leptospirosis were tested with the immunofluorescent antibody (IFA) assay and compared with the microscopic agglutination (MA) method. Overall, the IFA test recognized all 58 MA-positive patients with leptospirosis. On acute sera testing, the IFA titer > or = 1:100 was 0.97 specific and more sensitive than the conventional MA method (sensitivities = 0.48 versus 0.17, respectively). None of the 117 MA-negative patients, 101 healthy blood donors… CONTINUE READING

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