Evaluation of the genotoxic potential of lambda-cyhalothrin using nuclear and nucleolar biomarkers on fish cells.

@article{ava2003EvaluationOT,
  title={Evaluation of the genotoxic potential of lambda-cyhalothrin using nuclear and nucleolar biomarkers on fish cells.},
  author={Tolga Çavaş and Serap Ergene-G{\"o}z{\"u}kara},
  journal={Mutation research},
  year={2003},
  volume={534 1-2},
  pages={93-9}
}
Micronucleus formation in fish erythrocytes, as an indicator of chromosomal damage, has been increasingly used to detect the genotoxic potential of environmental contaminants. Nucleolar organizer regions (NORs) stained with colloidal silver techniques indicate sites of active RNA transcription. The number and size of NORs in interphase nuclei reflect cellular activities such as proliferation and differentiation of cells. In this study, nuclear (micronucleus frequency) and nucelolar (changes in… CONTINUE READING

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