Evaluation of the function of microdialysis probes permanently implanted into the rat CNS and coupled to an on-line HPLC system of analysis.

@article{Gerin1996EvaluationOT,
  title={Evaluation of the function of microdialysis probes permanently implanted into the rat CNS and coupled to an on-line HPLC system of analysis.},
  author={Claude Gerin and Alain Privat},
  journal={Journal of neuroscience methods},
  year={1996},
  volume={66 2},
  pages={81-92}
}
The aim of the microdialysis technique is to reflect as closely as possible the status and fluctuations of substances contained in the extracellular space. Most often, microdialysis is performed with repetitively implanted probes. We have recently devised an experimental set-up which allows microdialysis to be performed in the spinal cord of unrestrained rats through chronically permanently implanted probes. In the present study, we have compared the in vitro recovery of a non-biogenic amine… CONTINUE READING