Evaluation of the efficacy of memantine in the treatment of fibromyalgia: study protocol for a doubled-blind randomized controlled trial with six-month follow-up

@inproceedings{OlivnBlzquez2013EvaluationOT,
  title={Evaluation of the efficacy of memantine in the treatment of fibromyalgia: study protocol for a doubled-blind randomized controlled trial with six-month follow-up},
  author={B{\'a}rbara Oliv{\'a}n-Bl{\'a}zquez and Marta Puebla and B{\'a}rbara Masluk and Mar{\'i}a C P{\'e}rez-Yus and Raquel Arcega and Eva Andr{\'e}s and Yolanda L{\'o}pez-Del-Hoyo and R. Magall{\'o}n and Miquel Roca and Javier Garc{\'i}a-Campayo},
  booktitle={Trials},
  year={2013}
}
BACKGROUND Fibromyalgia is a prevalent chronic rheumatic disease of great clinical importance. Recent studies have found raised levels of glutamate in the insula, hippocampus and posterior cingulate cortex regions of the brains of fibromyalgia (FM) patients. This finding has led researchers to speculate about the usefulness of glutamate-blocking drugs such as memantine in the treatment of fibromyalgia. The hypothesis of this study is that the administration of memantine will reduce the… CONTINUE READING
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