Evaluation of the effects of botulinum toxin A injections when used to improve ease of care and comfort in children with cerebral palsy whom are non-ambulant: a double blind randomized controlled trial

@inproceedings{Thorley2012EvaluationOT,
  title={Evaluation of the effects of botulinum toxin A injections when used to improve ease of care and comfort in children with cerebral palsy whom are non-ambulant: a double blind randomized controlled trial},
  author={Megan Thorley and Samantha Donaghey and Priya Edwards and Lisa R Copeland and Megan J Kentish and Kim McLennan and Jayne Lindsley and Laura Gascoigne-Pees and Leanne Sakzewski and Roslyn N. Boyd},
  booktitle={BMC pediatrics},
  year={2012}
}
BACKGROUND Children with cerebral palsy (CP) whom are non-ambulant are at risk of reduced quality of life and poor health status. Severe spasticity leads to discomfort and pain. Carer burden for families is significant. This study aims to determine whether intramuscular injections of botulinum toxin A (BoNT-A) combined with a regime of standard therapy has a positive effect on care and comfort for children with CP whom are non-ambulant (GMFCS IV/V), compared with standard therapy alone (cycle I… CONTINUE READING
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