Evaluation of the effect of oxidative stress and vitamin E supplementation on renal function in rats with streptozotocin-induced Type 1 diabetes.

@article{Haidara2009EvaluationOT,
  title={Evaluation of the effect of oxidative stress and vitamin E supplementation on renal function in rats with streptozotocin-induced Type 1 diabetes.},
  author={Mohamed A. Haidara and Dimitri P. Mikhailidis and Moshira Abdelhakiim Rateb and Zeinab A Ahmed and Hanaa Z Yassin and Ibrahim Mearaj Ibrahim and Laila Ahmed Rashed},
  journal={Journal of diabetes and its complications},
  year={2009},
  volume={23 2},
  pages={130-6}
}
UNLABELLED We investigated the possible role of reactive oxygen species (ROS) on renal function in experimental diabetes. MATERIALS AND METHODS Seven groups of male rats were studied. Group I consisted of control animals. Diabetes was induced (by streptozotocin) in the animals in the other groups and they received either insulin or vitamin E (300 or 600 mg/kg), both insulin and vitamin E, or no treatment for 4 weeks. At the end of the study, blood pressure was measured and parameters of… CONTINUE READING