Evaluation of the effect of food and specific gravity of tablets on gastric retention time

@inproceedings{Sangekar1987EvaluationOT,
  title={Evaluation of the effect of food and specific gravity of tablets on gastric retention time},
  author={Surendra A. Sangekar and Winston A. Vadino and I Chaudry and Alan Parr and Robert M. Beihn and George A. Digenis},
  year={1987}
}
Abstract In the present study the effect of food and specific gravity on the gastric retention time of floating (spec. grav. 0.96) and non-floating (spec. grav. 1.59) tablet formulations was investigated using gamma scintigraphy in humans. The results obtained indicate that the presence of food in the stomach appears to significantly prolong gastric retention of both the floating and non-floating tablets while specific gravity does not seem to play an important role in the residency time of the… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 31 CITATIONS

Floating Systems for Oral Controlled Release Drug Delivery

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Formulation a Effervescent Tablets

VIEW 1 EXCERPT
CITES BACKGROUND

Application of an anionic polymer in the formulation of floating tablets containing an alkaline model drug.

  • Advances in clinical and experimental medicine : official organ Wroclaw Medical University
  • 2017