Evaluation of the dose metric for acute lung inflammogenicity of fast-dissolving metal oxide nanoparticles.

Abstract

Although surface area metric was suggested as an appropriate dose metric for acute lung inflammation of NPs, it might not be effective for fast-dissolving NPs because they lose their reactive surface when dissolved in the phagolysosomes. Herein, we evaluated the dose metric for fast-dissolving NPs using a rat intratracheal instillation model. A panel of… (More)

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Cite this paper

@article{Jeong2016EvaluationOT, title={Evaluation of the dose metric for acute lung inflammogenicity of fast-dissolving metal oxide nanoparticles.}, author={Jiyoung Jeong and Seonghan Lee and Sung-Hyun Kim and Youngju Han and Dong-Keon Lee and Jun Yang and Jayoung Jeong and Changhyun Roh and Yun Suk Huh and Wan-Seob Cho}, journal={Nanotoxicology}, year={2016}, volume={10 10}, pages={1448-1457} }