Evaluation of the diagnostic potential of region of deletion-1-encoded antigen culture filtrate protein-10 in pulmonary tuberculosis.

@article{Murthy2007EvaluationOT,
  title={Evaluation of the diagnostic potential of region of deletion-1-encoded antigen culture filtrate protein-10 in pulmonary tuberculosis.},
  author={Madhan Kumar Murthy and Ramana Rao V Parasa and Anbarasu Deenadayalan and Pawan Sharma and A. Mani Muthu Raja},
  journal={Diagnostic microbiology and infectious disease},
  year={2007},
  volume={59 3},
  pages={295-302}
}
The ability of region of deletion-1 (RD-1)-encoded culture filtrate protein-10 (CFP-10) to supplement the sensitivity of 38-kDa antigen was studied using enzyme-linked immunosorbent assay in pulmonary tuberculosis (TB) patients and controls. The sensitivities for individual antigens ranged from 50% to 60%, and the specificity was 100% for immunoglobulin (Ig) G alone. When IgA results were added to IgG, the sensitivity increased. On combination of the isotype results, sensitivity increased to 61… CONTINUE READING